Official Program
Note: All talks will be in ARMS 1010
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May 9
8:00 AM – 9:20 AM
Breakfast, Check-in and Poster Setup
9:20 AM – 9:30 AM
Opening Remarks by Aaron Krabill
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Session 1: Disease, Pathogenesis and Therapeutics (Chair: Anna Ratliff)
9:30 AM – 9:55 AM
Carbonic Anhydrase Inhibitors Curb Vancomycin-Resistant Enterococci Gut Colonization Through a Unique Target
Ahmed Hassan (Graduate student in Department of Comparative Pathobiology at Purdue University)
9:55 AM – 10:20 AM
Complete Protection Against a Potentially Pandemic H5N1 Influenza Virus Using a Bovine Adenoviral Vector-Based Vaccine
Ekramy Sayedahmed (Graduate student in Department of Comparative Pathobiology at Purdue University)
10:20 AM – 10:45 AM
Targeting the Main Carbon-Carbon Bond-Forming Machinery in Lipid Biosynthesis
Lee Stunkard (Graduate student in Department of Biochemistry at Purdue University)
10:45 AM – 11:10 AM
Coffee Break
Session 2: Biophysical Methods and Emerging Techniques (Chair: Matthew Pharris)
11:10 AM – 11:35 AM
Introducing Cryo-EM Virtual Reality Training & Outreach Tool
Brenda Gonzalez (Graduate student in Department of Biological Sciences at Purdue University)
11:35 AM – 12:00 AM
Engineering Glucose Binding Proteins with a Chemo-Enzymatic Tag for Glucose Detection
Divya Tankasala (Graduate student in Department of Biomedical Engineering at Purdue University)
12:00 AM – 12:25 PM
Toehold-Mediated DNA Strand Displacement Reactions for Specific and Sensitive Disease Detection
Elizabeth Phillips (Graduate student in Department of Biomedical Engineering at Purdue University)
12:25 PM – 1:10 PM
Lunch & Talks
12:45 pm - 1:05 pm
Chris Waddling - TTP Labtech
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Session 3: Investigations in Structural Biology I (Chair: Emma Lendy)
1:15 PM – 1:40 PM
Budding Induces Asymmetry into Flavivirus Virions
Matt Therkelsen (Graduate student in Department of Biological Sciences at Purdue University)
1:40 PM – 2:05 PM
Conformational Dynamics Contribute to Regulation of Phospholipase Cϵ
Liz Garland-Kuntz (Research Associate in Department of Chemistry at Purdue University)
2:05 PM – 2:30 PM
2.9 Å Resolution Structure Determined With A Single Position Of Volta Phase Plate
Chen Sun (Graduate student in Department of Biological Sciences at Purdue University)
2:30 PM – 2:55 PM
Structure of MERS Viral Protease Bound to the Complete Human ISG15 Facilitates Functional Tools for Coronavirus Attenuation
Jozlyn Clasman (Graduate student in Department of Biological Sciences at Purdue University)
2:55 PM – 3:20 PM
Coffee Break
Session 4: Computational Biology (Chair: Taylor Bailey)
3:20 PM – 3:45 PM
Algorithm and Chimera Plugin of MAINMAST, de novo Main-Chain Tracing Method for EM maps
Genki Terashi & Yuhong Zha (Postdoctoral scholar in Department of Biological Sciences at Purdue University & Undergraduate student in Department of Computer Science at Purdue University)
3:45 PM – 4:10 PM
Protein Secondary Structure Detection in Medium to Low Resolution Cryo-Electron Microscopy Maps using Deep Learning
Sai Raghavendra Maddhuri (Graduate student in Department of Computer Science at Purdue University)
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4:10 PM – 4:30 PM
‘Fixing’ the Gateway Between Electron Microscopy and BSL3 Viruses
Amar Parvate (Graduate student in Department of Biological Sciences at Purdue University)
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4:30 PM – 6:30 PM
Poster Session and Reception:
Food and drinks while supplies last
7:00 PM
Networking Event:
Stacked Pickle - 516 Northwestern. Ave.
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May 10
8:30 AM – 9:30 AM
Breakfast
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Session 5: Biochemistry and Molecular Biology (Chair: Aaron Krabill)
9:30 AM – 9:55 AM
Characterization and Mutational Analysis of the Proposed Ste24p Substrate Binding Site
Chelsea Theisen (Graduate student in Department of Chemistry at Purdue University)
9:55 AM – 10:20 AM
Identification and Characterization of Micro-RNAs that Modify Acute Neutrophilic Migration and Inflammation
Alan Hsu (Graduate student in Department of Biological Sciences at Purdue University)
10:20 AM – 10:45 AM
Continuous Fluorescent Assay to Measure SidE Family Ubiquitin Ligase Activity
Kedar Puvar (Graduate student in Department of Chemistry at Purdue University)
10:45 AM – 11:10 AM
Aberrantly Expressed MicroRNAs Drive the Development of Acquired Erlotinib-Resistance in Non-Small Cell Lung Cancer (NSCLC)
Arpita Pal (Graduate Student in the Department of Biological Sciences at Purdue University)
11:10 AM – 11:30 AM
Coffee Break
11:30 AM – 12:30 PM
Keynote Presentation: Micro and millisecond motions in allostery and phosphoryl transfer
Dr. J. Patrick Loria - Yale University
12:30 PM – 1:30 PM
Lunch & Talks
12:50 PM - 1:10 PM
Andy Mesecar - Purdue University “StructureBio Facilities at Purdue”
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Session 6: Investigations in Structural Biology II (Chair: Yu-Chen Yen)
1:30 PM – 1:55 PM
Crystal Structure of the C-terminal Guanine Exchange Factor Module of Trio Reveals its Oncogenic Potential
Sumit Bandekar (Graduate student in Department of Medicinal Chemistry at University of Michigan)
1:55 PM – 2:20 PM
Structural Insight into Neisseria meningitidis Lactoferrin Binding Protein B’s Interaction with Human Lactoferrin
Ravi Yadav (Graduate student in Department of Biological Sciences at Purdue University)
2:20 PM – 2:45 PM
Structural Investigations of an Infectious Alphavirus
S. Saif Hasan (Postdoctoral scholar in Department of Biological Sciences at Purdue University)
2:45 PM – 3:10 PM
Structural Basis of the Interactions Between GPCRs and GPCR Kinases
Quiyan Chen (Postdoctoral scholar in Department of Biological Sciences at Purdue University)
3:10 PM – 3:30 PM
Closing Remarks, Awards, and Acknowledgements